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Insulin Antibody

Name of disease:

Insulin Antibody

ICD-10 diagnosis code:

E31.0

Causes:

Most cases of Insulin autoimmune syndrome are sporadic, which means they occur in people with no history of the disorder in their family. It is an autoimmune disease which may be triggered by drugs or viral infection。

Mode of inheritance:

It is mostly sporadic and is rarely inherited from parents in family.

Prevalence:

Unknown

Diagnosis:

The diagnosis of insulin autoimmune syndrome is based on blood tests including blood glucose level, insulin level after ruling other causes of low blood glucose level Specialized test for the presence of autoantibodies can also be conducted to confirm the diagnosis

Age of onset:

At any age but usually in adult

Common signs and symptoms:

Low blood glucose level Fatigue Sweating Fainting Lightheadedness and weakness Organ damage including pancreas may occur in severe cases

Available treatments (medicinal and non-medicinal):

Currently, dietary control with regular monitoring of blood glucose level is suggested for the affected individuals. Also, in more serious condition, treatment to remove insulin antibodies from blood can be considered.

Disease management tips:

Most people affected by insulin autoimmune syndrome find that their symptoms go away after a few months. To avoid the low blood glucose level, patients are suggested to have smaller and more frequent meals in order to maintain a more consistent blood sugar level In serious cases, patients may have pancreas damage and treatment is required. If the disease is triggered by medications, patients should stop taking that medication.

References:

https://rarediseases.info.nih.gov/diseases/10808/insulin-autoimmune-syndrome https://rarediseases.info.nih.gov/diseases/10808/insulin-autoimmune-syndrome

Other useful websites:

Patient groups: American Autoimmune Related Diseases Association https://www.aarda.org/